What it can mean
Deep, central low back pain can sometimes be associated with damage or inflammation at the vertebral endplates. Sitting, bending, or lifting may aggravate symptoms, but these features overlap with other causes.
How it is evaluated
MRI may show Modic type 1 or type 2 endplate changes. These findings must be interpreted with the history and examination; they do not prove the pain source by themselves.
How care is planned
Conservative care is reviewed first. Basivertebral nerve ablation may be considered when symptoms, imaging, and treatment history meet the relevant selection criteria.
Further reading: Johns Hopkins Spine Center